Goals

1. Elucidate mechanisms underlying communication between endocrine tissues and the CNS.
2. Understand how these circuits coordinate behavior and physiological responses and are disrupted in disease.

Approaches

1. In vivo single neuron recording using electrophysiological and imaging based approaches.
2. Associative and instrumental models of learning and memory.
3. Genetically targeted chemo- and opto-genetic manipulation of specific neuron types.
4. Bioinformatic and proteomic analysis of endocrine-CNS signaling pathways.